Pediatric Graves’ Disease

Article Information

Article Type: Review article

Citation: Bansal S, Umpaichitra V, Desai N, PerezColon S (2015) Pediatric Graves’ Disease. Int J Endocr Metab Disord 1 (1): doi http://dx.doi.org/10.16966/ ijemd.104

Copyright:© 2015 Bansal S et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Publication history:

 Received date: 18 April, 2015

 Accepted date: 05 June, 2015

 Published date: 11 June, 2015

Authors

Shipra Bansal^1*#      Vatcharapan Umpaichitra^1#     Ninad Desai^2#      Sheila PerezColon^1*# 

¹Division of Pediatric Endocrinology, Kings County Hospital Center and SUNY Downstate Medical Center, Brooklyn, NY, USA
²Department of Pediatrics, Kings County Hospital Center and SUNY Downstate Medical Center, Brooklyn, NY, USA

# These authors contributed equally

*Corresponding author: Shipra Bansal, MBBS, Division of Pediatric Endocrinology, Department of Pediatrics, Kings County Hospital Center and SUNY Downstate Medical Center, 445 Lenox road, Box 49, Brooklyn, NY 11203, USA, Tel: 718 613 8605/8687; Fax: 718 613 8548; E-mail: shipra.bansal@downstate.edu

Sheila Perez-Colon, MD, Division of Pediatric Endocrinology, Department of Pediatrics, Kings County Hospital Center and SUNY Downstate Medical Center, 445 Lenox road, Box 49, Brooklyn, NY 11203, USA, Tel: 718 613 8605/8687; Fax: 718 613 8548; E-mail: sheila.perez-colon@ downstate.edu

Abstract

Graves’ disease is the most common cause of hyperthyroidism in children. It is characterized by suppressed thyroid stimulating hormone and elevated thyroxine levels with varying levels of thyroid stimulating immunoglobulins; and evidence of increased iodine uptake on thyroid scan. It is a multisystem disease with interplay of genetics and environmental factors. Due to the insidious onset of symptoms, diagnosis is often delayed leading to poor growth and development. The disorder could present at any age including neonatal period due to transfer of maternal antibodies in context of maternal Graves’ disease. Herein, we review the current literature for Graves’ disease affecting children and adolescents.

Keywords

Graves’ disease; Hyperthyroidism; Children; Adolescents


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